A INFECÇÃO PELO TRICHOMONAS VAGINALIS E SUAS POSSÍVEIS RELAÇÕES COM A AQUISIÇÃO E TRANSMISSÃO DO VÍRUS HIV

Rafael Euzébio

doi:10.37688/rcfu.v2i1.104

Rafael Euzébio UGB

DOI: https://doi.org/10.37688/rcfu.v2i1.104

Keywords: Trichomonas vaginalis, HIV, Trichomoniasis, Protozoan infection, Parasitology, STIs

Abstract

Trichomoniasis is an infection that affects men and women, caused by an anaerobic cosmopolitan protozoan, the Trichomonas vaginalis, which acts in the urogenital system for both men and women, being transmitted through sexual intercourse, making it the not viral sexually transmitted infection (STI) most common in the world, which is curable but can cause several damage to the human body. Although little valued, it has a great relation in acquiring and transmission of human immunodeficiency virus (HIV), and during the infection its pathogenicity influences responses in the immune system, where are the cells affected by HIV, occurring the infection of cells that end up facilitating the exposure of the virus. The purpose of this article is to understand the relationship between T. vaginalis and HIV. Virtual and printed books, and articles in Portuguese, Spanish and English were explored to shape the present bibliographic review. Trichomoniasis is often asymptomatic and easily transmitted between its partners. Campaigns are needed to guide the population about this STI.

References

ANDERSON, Brenna L. et al. Effect of trichomoniasis therapy on genital HIV viral burden among African women. Sexually transmitted diseases, v.39, n.8, p.638, 2012.

KUMAR et al. Robbins & Cotran Patologia - Bases Patológicas das Doenças. Editora Elsevier, 2010.

BENCHIMOL M. et al. Hydrogenosomes under microscopy. Tissue Cell, v.41, n.3, p.151-168, 2009.

BRITO, Ana Maria de et al. AIDS e infecção pelo HIV no Brasil: uma epidemia multifacetada. Rev. Soc. Bras. Med. Trop., Uberaba, v.34, n.2, p.207-217, abr. 2001.

BROTMAN, Rebecca M. et al. Association between Trichomonas vaginalis and vaginal bacterial community composition among reproductive-age women. Sexually transmitted diseases, v.39, n.10, 2012.

CARTER, J. Elliot; WHITHAUS, Kenneth C. Neonatal respiratory tract involvement by Trichomonas vaginalis: a case report and review of the literature. The American journal of tropical medicine and hygiene, v.78, n.1, p.17-19, 2008.

CHESSON, Harrell W. et al. The estimated direct medical cost of sexually transmitted diseases among American youth, 2000. Perspectives on sexual and reproductive health, v.36, n.1, 2004.

CHOSE O, Sarde et al. Cell death in protists without mitochondria. Annals of the New York Academy of Sciences, v.1010, p.121-125, dez. 2003.

DA COSTA, Rodrigo Furtado Madeiro et al. Trichomonas vaginalis perturbs the junctional complex in epithelial cells. Cell research, v.15, n.9, p.704-716, 2005.

CRUCITTI T, Jespers et al. Non-Sexual Transmission of Trichomonas vaginalis in Adolescent Girls Attending School in Ndola, Zambia. PLoS ONE, v.6, n.1, 2011.

CUDMORE, Sarah L. et al. Treatment of infections caused by metronidazole-resistant Trichomonas vaginalis. Clinical microbiology reviews, v.17, n.4, p.783-93, 2005.

DAVIS, Alissa et al. Trichomonas vaginalis and Human Immunodeficiency Virus Coinfection Among Women Under Community Supervision: A Call for Expanded T. vaginalis Screening. Sexually transmitted diseases, v.43, n.10, p.617-22, 2016.

DUBOUCHER, Christophe et al. Pulmonary coinfection by Trichomonas vaginalis and Pneumocystis sp. as a novel manifestation of AIDS. Human pathology, v.34, n.5, p.508-511, 2003.

FICHOROVA, Raina N. et al. Endobiont Viruses Sensed by the Human Host – Beyond Conventional Antiparasitic Therapy. PLoS ONE, v.7, n.11, 2012.

FICHOROVA, Raina N. Impact of T. vaginalis infection on innate immune responses and reproductive outcome. Journal of reproductive immunology, v.83, n.1-2, p.185-189, 2009.

OTAROLA U., Claudia et al. Frecuencia de tricomonas vaginalis detectadas mediante papanicolaou en cuatro servicios de salud, 1997-2002. Rev. chil. obstet. ginecol. Santiago, v.70, n.1, p.3-7, 2005.

GUENTHNER, Patricia C. et al. Trichomonas vaginalis-induced epithelial monolayer disruption and human immunodeficiency virus type 1 (HIV-1) replication: implications for the sexual transmission of HIV-1. Infection and immunity, v.73, n.7, p.4155-60, 2005.

HAMMERSCHLAG, Margaret R.; GUILLÉN, Christina D. Medical and legal implications of testing for sexually transmitted infections in children. Clinical microbiology reviews, v.23, n.3, p.493-506, 2010.

HUGHES, James P. et al. Determinants of per-coital-act HIV-1 infectivity among African HIV-1-serodiscordant couples. The Journal of infectious diseases, v.205, n.3, p.358-65, 2012.

JANEWAY, C. A.; TRAVERS, P.; WALPORT, M.; CAPRA, J. D. Imunobiologia: O Sistema Imunológico na Saúde e na Doença. Porto Alegre: Artmed, 2000.

KISSINGER, Patricia; ADAMSKI, Alys. Trichomoniasis and HIV interactions: a review. Sexually transmitted infections, v.89, n.6, p.426-33, 2013.

KISSINGER, Patricia et al. Trichomonas vaginalis treatment reduces vaginal HIV-1 shedding. Sexually transmitted diseases, v.36, n.1, p.11-6, 2009.

BACHMANN, Laura H. et al. Trichomonas vaginalis genital infections: progress and challenges. Clinical Infectious Diseases, v.53, n.3, p.S160-S172, 2011.

LEHKER, Michael W.; ALDERETE, John F. Biology of trichomonosis. Current opinion in infectious diseases, v.13, n.1, p.37-45, 2000.

LETERRIER, Marion et al. Trichomonads in pleural effusion: case report, literature review and utility of PCR for species identification. Microbiologica-Quarterly Journal of Microbiological Sciences, v.35, n.1, p.83, 2012.

MACIEL, Gisele de Paiva; TASCA, Tiana; DE CARLI, Geraldo Attilio. Clinical aspects, pathogenesis and diagnostic of Trichomonas vaginalis. Jornal Brasileiro de Patologia e Medicina Laboratorial, v.40, n.3, p.152-160, 2004.

MARITZ, Julia M. et al. What is the importance of zoonotic trichomonads for human health? Trends in parasitology, v.30, n.7, p.333-341, 2014.

MAVEDZENGE, Sue Napierala et al. Epidemiological synergy of Trichomonas vaginalis and HIV in Zimbabwean and South African women. Sexually transmitted diseases, v.37, n.7, p.460-466, 2010.

LÓPEZ, Luciene Bottentuit et al. Strategies by which some pathogenic trichomonads integrate diverse signals in the decision-making process. Anais da Academia Brasileira de Ciências, v.72, n.2, p.173-186, 2000.

MORTOZA JUNIOR, G. Doenças sexualmente transmissíveis. In: Manual do TEGO.

ed. Rio de Janeiro: Sociedade Brasileira de obstetrícia e ginecologia de Minas

Gerais, 2000.

NEVES, D. P. et al. Parasitologia Humana. 11. Ed. São Paulo: Editora Atheneu, 2005.

NIBALI, Luigi; HENDERSON, Brian (Ed.). The human microbiota and chronic disease: Dysbiosis as a cause of human pathology. John Wiley & Sons, 2016.

OLIVEIRA, Paula Matos et al. Vulvovaginites em mulheres infectadas pelo vírus da imunodeficiência humana. Revista Brasileira de Ginecologia e Obstetrícia, v.30, n.3, p.121-126, 2008.

KISSINGER, Patricia; ADAMSKI, Alys. Trichomoniasis and HIV interactions: a review. Sexually transmitted infections, v.89, n.6, p.426-433, 2013.

PAZ-BAILEY, Gabriela et al. Determinants of HIV type 1 shedding from genital ulcers among men in South Africa. Clinical infectious diseases, v.50, n.7, p.1060-1067, 2010.

PEREIRA-NEVES, Antonio; RIBEIRO, Karla Consort; BENCHIMOL, Marlene. Pseudocysts in trichomonads–new insights. Protist, v.154, n.3-4, p.313-329, 2003.

PETRIN, Dino et al. Clinical and microbiological aspects ofTrichomonas vaginalis. Clinical microbiology reviews, v.11, n.2, p.300-317, 1998.

POOLE, Danielle N.; MCCLELLAND, R. Scott. Global epidemiology of Trichomonas vaginalis. Sexually transmitted infections, v.89, n.6, p.418-422, 2013.

PRICE, Matthew A. et al. Addition of Treatment for Trichomoniasis to Syndromic Management of Urethritis in Malawi: A Randomized Clinical Trial. Sexually transmitted diseases, v.30, n.6, p.516-522, 2003.

QUINLIVAN, E. Byrd et al. Modeling the impact of Trichomonas vaginalis infection on HIV transmission in HIV-infected individuals in medical care. Sexually transmitted diseases, v.39, n.9, p.671, 2012.

MCCLELLAND, R. Scott et al. Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition. The Journal of infectious diseases, v.195, n.5, p.698-702, 2007.

READING, Richard et al. Gonorrhoea, chlamydia, syphilis and trichomonas in children under 13 years of age: national surveillance in the UK and Republic of Ireland. Archives of disease in childhood, v.99, n.8, p.712-716, 2014.

RIGO, Graziela Vargas et al. Diamine derivative anti-Trichomonas vaginalis and anti-Tritrichomonas foetus activities by effect on polyamine metabolism. Biomedicine & pharmacotherapy, v.95, p.847-855, 2917.

TRACY, J. W.; WEBSTER, L. T. Drugs used in the chemoterapy of protozoal infections. In: GOODMAN, Louis Sanford et al. Goodman and Gilman's the pharmacological basis of therapeutics. New York: McGraw-Hill, 1996.

VAN DER POL, Barbara et al. Trichomonas vaginalis infection and human immunodeficiency virus acquisition in African women. The Journal of infectious diseases, v.197, n.4, p.548-554, 2008.

WANG, Chia C. et al. The effect of treatment of vaginal infections on shedding of human immunodeficiency virus type 1. The Journal of infectious diseases, v.183, n.7, p.1017-1022, 2001.

WORLD HEALTH ORGANIZATION et al. Prevalence and incidence of selected sexually transmitted infections, Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis and Trichomonas vaginalis: methods and results used by WHO to generate 2005 estimates. World Health Organization, 2011.